Life and Health Today
Health and longevity news for everyday readers, published daily from the United States: regenerative medicine, longevity research, exercise and nutrition science, and biohacking. Reported from the research and from the agencies that regulate it, in plain language, alongside a curated feed of the day's coverage elsewhere, each item linking to the publication that reported it.
Latest articles
- Early-onset Alzheimer's shows faster, wider tau buildup than late-onset disease Longevity
A study of 601 Alzheimer's patients found that those diagnosed before age 65 accumulated tau protein more rapidly and across more of the brain than patients diagnosed later in life. The difference...
- Microsoft outage hit NHS email but clinical systems held Biohacking
A global Microsoft failure that began Thursday evening knocked out email across multiple NHS trusts and slowed pharmacy communications, while clinical and emergency systems largely stayed up....
- Gene study in 100,000 Americans finds drug-response variants missed by earlier research Longevity
A large genomic study found that every one of nearly 100,000 participants carried at least one variant in genes that shape how the body processes common prescription drugs. Because the group was...
- Twenty years in, iPSC technology is moving from lab tool toward the clinic Regenerative
Induced pluripotent stem cells, the reprogrammed adult cells that Shinya Yamanaka's team first described in 2006, are now the foundation of disease modeling, drug discovery and early cell therapy...
- Vitamin D2 vs. D3: What's the Difference? Longevity
Both forms of vitamin D can raise your levels, but they come from different sources and are not equally effective. Here is how D2 and D3 differ, how much adults need, and why most studies favor D3...
- FDA proposes easing approval rules for cancer-diagnostic lab tests Longevity
The Food and Drug Administration is proposing to move a category of cancer-related diagnostic tests from its most stringent approval pathway to a lighter one. The change would affect...
- MDCalc's new tool strips patient data from AI queries before they leave the clinic Biohacking
MDCalc, a widely used medical reference site, has launched a tool called CrossCover that removes identifying patient information from clinicians' AI queries rather than brokering privacy...
- Brain fluid drainage stalls in Alzheimer's, mouse study finds a cholesterol link Longevity
Cerebrospinal fluid, the clear liquid that washes waste from brain tissue during sleep, appears to stagnate in Alzheimer's disease. New research in mice points to disrupted cholesterol metabolism...
- Alzheimer's risk gene CASS4 directs immune cells to compress toxic plaques, mouse study finds Longevity
Researchers at the University of Virginia School of Medicine have established what the CASS4 gene does in the brain: it instructs microglia, the brain's resident immune cells, to surround and...
- Breast cancer chemo may cost survivors nearly a decade of healthy life, simulation finds Longevity
A population-level simulation by Georgetown University researchers estimates that the most aggressive breast cancer chemotherapy regimens could strip an average of 9.4 years of healthy life from...
- Dutch and Italian regulators probe Biogen over MS blood test access Longevity
Antitrust authorities in two countries are investigating whether Biogen restricted a safety test for its multiple sclerosis drug Tysabri to patients on its own product, shutting out users of a...
- Democratic wins put Medicaid expansion back on the table in Texas, Georgia and Wisconsin Longevity
Midterm elections shifted power in three of the ten states that have never expanded Medicaid under the Affordable Care Act. Newly elected Democratic governors in all three campaigned on expansion,...
- A protein in muscle cells may help explain why exercise fights type 2 diabetes Longevity
Researchers found that a protein called Miro1 accumulates in the skeletal muscles of people with type 2 diabetes and appears to block the body's response to insulin. In a small randomized trial of...
- Blood tests cover about a quarter of what doctors want to know about your health Longevity
Physician Peter Attia estimates that even a comprehensive blood panel gives a clinician somewhere between 25 and 30 percent of the information needed to assess health risk fully. The rest comes...
- Going lower on blood pressure helps stroke survivors but not diabetic patients, trials find Longevity
Three trials presented at the American Heart Association's 2026 scientific sessions tested whether pushing blood pressure below standard targets reduces heart attacks, strokes and deaths. The...
- Ziltivekimab cut inflammation but not heart events in a 6,376-patient trial Longevity
Novo Nordisk's ZEUS trial tested whether blocking the inflammatory protein interleukin-6 could reduce heart attacks, strokes and cardiovascular deaths in people with established heart disease and...
- Two large heart drug trials failed despite genetic logic backing them Longevity
A Novartis drug that lowered a blood protein linked by genetics to heart risk did not reduce heart attacks or strokes in a large trial. A Novo Nordisk anti-inflammatory targeting a different...
- FDA clears bladder-cancer implant after 82% response rate in trial Regenerative
A slow-release gemcitabine device placed directly inside the bladder won full FDA approval in September 2025 for patients whose cancer stopped responding to the standard BCG treatment. In a...
- Pressing on mouse shinbones extended median lifespan by 9.4%, pointing to a bone-based aging pathway Longevity
Scientists at Southern Medical University in Guangzhou applied rhythmic mechanical pressure to the shinbones of elderly mice and found it extended their median lifespan by 9.4 percent, or roughly...
- One CRISPR shot cut LDL cholesterol by half in 15 people, with caveats Regenerative
A first-in-human trial of a gene-editing therapy called CTX310 reduced LDL cholesterol and triglycerides by roughly 50 percent on average at the highest dose tested, Cleveland Clinic researchers...
- Resistance training linked to sharper processing speed in midlife women, study finds Performance
A cross-sectional study of 93 women aged 35 to 63 found that regular exercise was associated with slower age-related decline in processing speed and working memory, with resistance training...
- Naked mole rat genes slow aging in mice, but human use is far off Longevity
Scientists are beginning to transplant genes from one of nature's longest-lived rodents into other species, with early results in mice showing reduced tumors and longer lives. The work, reviewed...
- One American's health costs in Malta vs. the U.S., by the numbers Longevity
Mariska Breland has multiple sclerosis, a history of breast cancer, and half a liver. When her husband left federal employment and the couple priced exchange coverage in New York for 2026, the...
- Age-adjusted death rates 19.2% higher in Trump-voting states than Harris-voting states, UCSF researchers find Longevity
An analysis of publicly available mortality data by researchers at the University of California San Francisco found that age-adjusted death rates were 19.2% higher in states that voted for Donald...
- Two biotech firms are building shared tools to move cell therapies from lab to clinic Regenerative
Manufacturing a cell therapy is not like making a pill: every patient's cells behave differently, and scaling that process reliably is one of the field's hardest unsolved problems. FUJIFILM...
- Kymera's pill-based eczema drug faces its biggest test yet against Dupixent Regenerative
Massachusetts biotech Kymera Therapeutics is set to release mid-stage trial results for KT-621, an experimental eczema treatment, before the end of 2026. The drug works differently from the...
- Prenatal therapy linked to smaller infant brain region, meaning unknown Longevity
Babies born to mothers who received talk therapy for depression during pregnancy had smaller right hippocampal volumes at six weeks than babies whose mothers received standard care, according to a...
- Global hypertension guidelines split treatment into two tiers by resource level Longevity
The International Society of Hypertension has updated its global blood pressure guidelines for the first time since 2020, organizing care into essential and optimal tiers so clinicians in...
- Non-hormonal menopause drugs ease sleep problems in meta-analysis of 3,184 women Longevity
A meta-analysis of seven randomized controlled trials found that two FDA-approved non-hormonal drugs reduced sleep disturbance in menopausal women with moderate-to-severe hot flashes, with...
- GLP-1 users report nail detachment at four times the rate of non-users Longevity
A multinational controlled study found that people taking GLP-1 drugs such as Ozempic and Wegovy were far more likely to report nail separation, discoloration, hair loss and scalp inflammation...
- Low muscle strength plus obesity linked to worse cognition in older adults Longevity
A study of 366 older adults in Taiwan found that those with sarcopenic obesity or dynapenic obesity scored lower on tests of global cognition, memory and attention than those without these...
- Walking while thinking may flag early cognitive decline, 22-year review finds Longevity
A bibliometric analysis of 1,347 studies in GeroScience traces how dual-task testing, asking someone to walk and think at the same time, has evolved from a simple gait measure into a candidate...
- IgG food sensitivity tests do not identify what is making athletes sick Performance
Home blood tests that promise to pinpoint the foods behind bloating, fatigue and poor recovery are widely used by athletes, but professional allergy organisations say they measure the wrong thing....
- Lysosomes build up waste as they age, and researchers can now measure it Longevity
A new study mapped how the cell's recycling centers change chemically across age, species and tissues, finding a consistent molecular pattern that tracks closely enough with time to function as a...
- Longer ureteral stents in children tied to higher infection risk despite antibiotics Regenerative
More than a quarter of children with internal kidney-drainage tubes developed urinary tract infections even while taking daily preventive antibiotics, a study in the Journal of Pediatric Urology...
- More daily steps linked to better teen mental health and brain structure, study finds Performance
A study of 5,515 American adolescents found that higher daily step counts were associated with fewer symptoms of depression and anxiety one year later. Researchers at King's College London and the...
- ChatGPT answered IVF questions accurately but left gaps doctors flagged Biohacking
A small comparative analysis presented at the American Society for Reproductive Medicine's annual meeting found that ChatGPT's responses to common IVF questions scored lower than professional...
- Sesame compound eased alcohol-related gut aging in middle-aged mice Longevity
A sesame-derived compound called sesaminol reduced signs of intestinal aging and inflammation in middle-aged mice given alcohol daily for ten weeks, according to a study published in GeroScience....
- Male tree shrews outlived females by median lifespan in first detailed captive colony study Longevity
Researchers at the University of Alabama at Birmingham tracked their Northern tree shrew colony and found males had a longer median lifespan than females, though maximum lifespan and mortality...
- FDA proposes updating nutrient rules for infant formula in phased review Longevity
The Food and Drug Administration published a proposed rule on October 29, 2026, that would adjust required levels for four of the roughly 30 nutrients infant formula must contain, update labeling...
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